CD46

Across TCGA patient cohorts, CD46 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,839 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CD46-associated proteins across cancer lineages are ATP1A1, CD9, and ATP1B1. Each is linked with CD46 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD46-to-partner and partner-to-CD46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD46 versus ATP1A1 in UCEC, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD46→partner) and Y-score (partner→CD46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP1A1 →	+0.702	+0.712	<.001	<.001	3	9
UCEC	CD9 →	+0.776	+0.693	<.001	<.001	3	9
PDAC	ATP1B1 →	+0.757	+0.600	<.001	<.001	3	8
UCEC	F11R →	+0.655	+0.805	<.001	<.001	3	8
PDAC	ATP2B4 →	+0.554	+0.617	<.001	<.001	3	7
UCEC	ADAM15 →	+0.534	+0.817	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,839 associations by consensus.

CD46 vs ATP1A1 — UCEC

Explore this scatter interactively →