CD40LG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD40LG RNA expression is significantly associated with the protein abundance of many other proteins, with 21,474 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD40LG-associated proteins across cancer lineages are CD48, COTL1, and FNBP1. Each is linked with CD40LG in more than 8 cancer types. Because this analysis shows association rather than direction, both CD40LG-to-partner and partner-to-CD40LG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD40LG versus CD48 in UCEC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD40LG→partner) and Y-score (partner→CD40LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD48 →+1.069+1.013<.001<.00139
LSCCCOTL1 →+0.615+0.852<.001<.00139
HNSCFNBP1 →+0.569+0.832<.001<.00139
OVABI3 →+0.696+0.776<.001<.00139
HNSCHCLS1 →+0.656+0.957<.001<.00139
LSCCSEPTIN1 →+0.971+0.868<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,474 associations by consensus.

CD40LG vs CD48 — UCEC

Per-sample scatter of CD40LG vs CD48 in UCEC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration