CD40LG

Across TCGA cell cohorts, CD40LG mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD40LG-associated genes across cancer lineages are MROH2B. Each is linked with CD40LG in more than 1 cancer types. Because this analysis shows association rather than direction, both CD40LG-to-partner and partner-to-CD40LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MROH2B grouped by CD40LG-low versus CD40LG-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD40LG→partner) and Y-score (partner→CD40LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MROH2B →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MROH2B by CD40LG expression — LARGE_INTESTINE

Explore this box plot interactively →