CD40

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD40 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,846 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD40-associated proteins across cancer lineages are RENBP, SERPINB9, and DEF6. Each is linked with CD40 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD40-to-partner and partner-to-CD40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD40 versus RENBP in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD40→partner) and Y-score (partner→CD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRENBP →+0.572+0.564<.001<.00139
OVSERPINB9 →+0.564+1.238<.001<.00139
GBMDEF6 →+0.566+0.751<.001<.00139
BRCADPYD →+0.623+0.997<.001<.00139
GBMHCLS1 →+0.705+0.845<.001<.00139
GBMMYO1G →+0.596+0.726<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,846 associations by consensus.

CD40 vs RENBP — GBM

Per-sample scatter of CD40 vs RENBP in GBM (Pearson r = 0.40).

Explore this scatter interactively →

Exploration