CD40

Across TCGA patient cohorts, CD40 protein abundance is significantly associated with the RNA expression of many other genes, with 13,508 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD40-associated genes across cancer lineages are VAV1, CSF2RB, and IL21R. Each is linked with CD40 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD40-to-partner and partner-to-CD40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD40 versus VAV1 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD40→partner) and Y-score (partner→CD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VAV1 →	+0.855	+0.624	<.001	<.001	3	9
COAD	CSF2RB →	+1.357	+0.765	<.001	<.001	3	8
UCEC	IL21R →	+0.824	+0.661	<.001	<.001	3	8
COAD	IL4I1 →	+1.602	+0.817	<.001	<.001	3	8
COAD	LILRB1 →	+1.190	+0.830	<.001	<.001	3	8
COAD	TFEC →	+1.357	+0.750	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,508 associations by consensus.

CD40 vs VAV1 — UCEC

Explore this scatter interactively →