CD40

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD40 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,220 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CD40-associated proteins across cancer lineages are CD163, APBB1IP, and RHOG. Each is linked with CD40 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD40-to-partner and partner-to-CD40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD40 versus CD163 in GBM, with a Pearson correlation of 0.37.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD40→partner) and Y-score (partner→CD40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCD163 →+1.006+0.625<.001<.00139
GBMAPBB1IP →+0.851+0.752<.001<.00139
OVRHOG →+0.552+1.010<.001<.00139
GBMTNFAIP8 →+0.464+0.429.001.00139
UCECCD53 →+0.977+1.004<.001<.00139
COADDOCK10 →+0.625+0.667<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,220 associations by consensus.

CD40 vs CD163 — GBM

Per-sample scatter of CD40 vs CD163 in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration