Across TCGA patient cohorts, CD3E RNA expression is significantly associated with the protein abundance of many other proteins, with 18,837 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD3E-associated proteins across cancer lineages are RCSD1, SAMSN1_S23, and SASH3. Each is linked with CD3E in more than 9 cancer types. Because this analysis shows association rather than direction, both CD3E-to-partner and partner-to-CD3E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3E→partner) and Y-score (partner→CD3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCSD1 →	+0.609	+0.902	<.001	<.001	3	10
BRCA	SAMSN1_S23 →	+0.930	+1.303	<.001	<.001	3	10
LSCC	SASH3 →	+0.505	+1.015	<.001	<.001	3	10
BRCA	SEPTIN1 →	+0.999	+1.696	<.001	<.001	3	10
GBM	WAS →	+0.630	+0.913	<.001	<.001	3	10
LSCC	WDFY4 →	+0.557	+1.055	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,837 associations by consensus.

Exploration

CD3E survival (RNA) · tumor vs normal (RNA) · all CD3E data types