Across TCGA cell cohorts, CD3E RNA expression is significantly associated with the go_rna of many other GO terms, with 2,628 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD3E-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with CD3E in more than 8 cancer types. Because this analysis shows association rather than direction, both CD3E-to-partner and partner-to-CD3E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3E→partner) and Y-score (partner→CD3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.098	+0.135	<.001	<.001	3	9
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.107	+0.145	<.001	<.001	3	9
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.090	+0.138	.007	.003	2	9
PANCREAS	Regulation of myoblast fusion →	+0.091	+0.135	.007	.004	2	8
PANCREAS	ERBB3 signaling pathway →	+0.163	+0.148	.001	.004	3	7
PANCREAS	ERBB2-ERBB3 signaling pathway →	+0.163	+0.148	.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,628 associations by consensus.

Exploration

CD3E survival (RNA) · tumor vs normal (RNA) · all CD3E data types