CD38

Across TCGA patient cohorts, CD38 protein abundance is significantly associated with the RNA expression of many other genes, with 23,105 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD38-associated genes across cancer lineages are TLR10, IGKV1D-8, and SP140. Each is linked with CD38 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD38-to-partner and partner-to-CD38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD38 versus TLR10 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD38→partner) and Y-score (partner→CD38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TLR10 →	+0.988	+0.771	<.001	<.001	3	10
LSCC	IGKV1D-8 →	+1.871	+1.064	<.001	<.001	3	10
LSCC	SP140 →	+1.052	+0.926	<.001	<.001	3	10
BRCA	APOBEC3H →	+0.679	+0.822	<.001	<.001	3	9
UCEC	SLA2 →	+1.075	+1.018	<.001	<.001	3	9
HNSC	PIM2 →	+1.515	+1.064	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,105 associations by consensus.

CD38 vs TLR10 — LSCC

Explore this scatter interactively →