CD37

Across TCGA cell cohorts, CD37 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,422 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CD37-associated GO terms across cancer lineages are Positive regulation of DNA recombination, Positive regulation of double-strand break repair, and Thigmotaxis. Each is linked with CD37 in more than 10 cancer types. Because this analysis shows association rather than direction, both CD37-to-partner and partner-to-CD37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA recombination grouped by CD37-low versus CD37-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD37→partner) and Y-score (partner→CD37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA recombination →	+0.122	+1.166	<.001	.006	3	11
STOMACH	Positive regulation of double-strand break repair →	+0.073	+1.122	.004	.001	2	11
SOFT_TISSUE	Thigmotaxis →	+0.232	+2.007	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of transcription by RNA polymerase I →	+0.127	+1.308	<.001	<.001	3	10
BONE	Positive regulation of DNA repair →	+0.077	+1.303	<.001	.001	3	9
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.044	+1.189	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,422 associations by consensus.

Positive regulation of DNA recombination by CD37 expression — BONE

Explore this box plot interactively →