CD34

Across TCGA cell cohorts, CD34 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,633 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CD34-associated GO terms across cancer lineages are Golgi vesicle transport, Protein localization to vacuole, and Negative regulation of myoblast fusion. Each is linked with CD34 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD34-to-partner and partner-to-CD34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by CD34-low versus CD34-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD34→partner) and Y-score (partner→CD34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Golgi vesicle transport →	+0.106	+0.240	.003	.008	3	10
BONE	Protein localization to vacuole →	+0.084	+0.706	.001	.007	3	8
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.180	+0.275	<.001	.003	3	8
OESOPHAGUS	Cytoplasmic translation →	+0.140	+0.277	<.001	.003	3	8
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.182	+0.275	<.001	.003	3	8
LARGE_INTESTINE	Schwann cell differentiation →	+0.082	+0.153	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,633 associations by consensus.

Golgi vesicle transport by CD34 expression — OESOPHAGUS

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