CD33

Across TCGA patient cohorts, CD33 protein abundance is significantly associated with the RNA expression of many other genes, with 9,085 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD33-associated genes across cancer lineages are MYO1F, CD14, and CMKLR1. Each is linked with CD33 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD33-to-partner and partner-to-CD33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD33 versus MYO1F in UCEC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD33→partner) and Y-score (partner→CD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO1F →	+0.924	+0.786	.001	.001	3	6
GBM	CD14 →	+1.066	+0.640	<.001	<.001	3	6
UCEC	CMKLR1 →	+1.583	+0.827	.002	.002	3	6
CCRCC	CYTH4 →	+0.921	+0.848	.006	.007	3	5
OV	LYL1 →	+0.793	+0.598	.002	.001	3	5
OV	BIN2 →	+1.028	+0.706	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,085 associations by consensus.

CD33 vs MYO1F — UCEC

Explore this scatter interactively →