CD33

Across TCGA patient cohorts, CD33 mutation is significantly associated with the RNA expression of many other genes, with 3,816 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD33-associated genes across cancer lineages are LINC02210-CRHR1, MIR1255B2, and GPATCH11. Each is linked with CD33 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD33-to-partner and partner-to-CD33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02210-CRHR1 grouped by CD33-low versus CD33-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD33→partner) and Y-score (partner→CD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02210-CRHR1 →	+0.353	+2.609	<.001	.006	3	4
HNSC	MIR1255B2 →	+0.566	+5.468	<.001	.002	3	3
UCEC	GPATCH11 →	+0.405	+2.279	.001	<.001	3	3
LUAD	CCDC62 →	+0.212	+3.334	.002	.007	3	3
LUAD	OR6C68 →	+0.017	+4.108	.006	.007	3	3
COAD	RNA5SP237 →	+0.431	+4.308	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,816 associations by consensus.

LINC02210-CRHR1 by CD33 expression — LUAD

Explore this box plot interactively →