Across TCGA pan-cancer cohorts, CD300LG Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CD300LG data layer compared with 27 for mass-spec protein.
The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CD300LG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CD300LG expression acts as an unfavorable survival marker, although some lineages such as LUSC and UCEC show a favorable association.
SKCM, SARC, and LUSC are the cancer types where CD300LG Mutation most reproducibly stratifies survival.