CD300LG

Across TCGA patient cohorts, CD300LG mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300LG-associated genes across cancer lineages are Caspase-7-cleavedD198, S6, and 14-3-3_beta. Each is linked with CD300LG in more than 3 cancer types. Because this analysis shows association rather than direction, both CD300LG-to-partner and partner-to-CD300LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CD300LG-low versus CD300LG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LG→partner) and Y-score (partner→CD300LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.678	+2.479	.003	.010	3	4
SKCM	S6 →	-0.525	-3.000	.041	.036	3	1
UCEC	14-3-3_beta →	-0.114	-2.432	.003	.018	3	1
UCEC	eIF4E →	+0.237	+3.459	.004	.005	2	2
UCEC	JNK2 →	+0.315	+2.502	<.001	.002	3	1
UCEC	mTOR →	-0.144	-1.584	.023	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Caspase-7-cleavedD198 by CD300LG expression — UCEC

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