CD300LG

Across TCGA cell cohorts, CD300LG mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD300LG-associated genes across cancer lineages are MS4A6E, C16orf82, and KRTAP10-11. Each is linked with CD300LG in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300LG-to-partner and partner-to-CD300LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A6E grouped by CD300LG-low versus CD300LG-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LG→partner) and Y-score (partner→CD300LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MS4A6E →	+0.044	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	C16orf82 →	+0.013	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP10-11 →	+0.018	+4.887	<.001	.009	3	1
SKIN	IFNK →	+0.096	+4.095	<.001	.009	3	1
LARGE_INTESTINE	HTR1E →	+0.085	+3.930	<.001	.003	3	1
LARGE_INTESTINE	ADIPOQ →	+0.013	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MS4A6E by CD300LG expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →