CD300LF

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD300LF mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300LF-associated genes across cancer lineages are Chk1, MEK1, and Akt. Each is linked with CD300LF in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300LF-to-partner and partner-to-CD300LF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LF→partner) and Y-score (partner→CD300LF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMChk1 →+0.242+2.824.020.03432
UCECMEK1 →+0.405+3.584.011.00232
UCECAkt →-0.209-2.311.036.03432
UCECPDCD4 →-0.633-3.169.002.01832
UCECEGFR_pY1068 →-0.247-2.115.024.01922
UCECERK2 →+0.225+2.807.007.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration