CD300LB

Across TCGA patient cohorts, CD300LB mutation is significantly associated with the RNA expression of many other genes, with 1,337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300LB-associated genes across cancer lineages are TMEM269, MIR6839, and ZNF123P. Each is linked with CD300LB in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300LB-to-partner and partner-to-CD300LB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM269 grouped by CD300LB-low versus CD300LB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LB→partner) and Y-score (partner→CD300LB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM269 →	+0.272	+3.739	<.001	<.001	3	2
LUSC	MIR6839 →	+0.454	+3.517	<.001	.006	3	2
LIHC	ZNF123P →	+0.033	+4.964	.005	.002	3	2
UCEC	AOC2 →	+1.437	+3.906	<.001	<.001	3	2
UCEC	KLHL36 →	+0.489	+3.600	<.001	.001	3	2
UCEC	ZCCHC14 →	+0.481	+3.470	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,337 associations by consensus.

TMEM269 by CD300LB expression — UCEC

Explore this box plot interactively →