CD300E

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD300E mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300E-associated genes across cancer lineages are Notch1, p21, and PCNA. Each is linked with CD300E in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300E-to-partner and partner-to-CD300E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300E→partner) and Y-score (partner→CD300E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.204+2.321.003.03531
UCECp21 →+0.199+3.013.040.01831
UCECPCNA →+0.217+3.459.046.00531
UCECCaspase-8 →-0.267-2.973.034.03531
UCECcIAP →+0.139+2.348.044.01931
UCECCyclin-B1 →+0.852+2.321.002.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration