CD300C

Across TCGA patient cohorts, CD300C mutation is significantly associated with the RNA expression of many other genes, with 2,147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300C-associated genes across cancer lineages are TUBGCP5, PIGW, and COMMD4. Each is linked with CD300C in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300C-to-partner and partner-to-CD300C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP5 grouped by CD300C-low versus CD300C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300C→partner) and Y-score (partner→CD300C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBGCP5 →	+0.481	+2.534	<.001	.001	3	2
UCEC	PIGW →	+0.550	+2.513	.004	.001	3	2
SKCM	COMMD4 →	+0.493	+3.350	.001	.005	3	2
UCEC	OXSM →	+0.438	+3.516	<.001	.002	3	2
SKCM	EXOG →	+0.442	+3.478	.006	.002	3	2
SKCM	RAB27A →	+0.977	+2.706	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,147 associations by consensus.

TUBGCP5 by CD300C expression — UCEC

Explore this box plot interactively →