CD300C

Across TCGA patient cohorts, CD300C mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300C-associated genes across cancer lineages are ERK2, EGFR_pY1068, and JNK2. Each is linked with CD300C in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300C-to-partner and partner-to-CD300C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by CD300C-low versus CD300C-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300C→partner) and Y-score (partner→CD300C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ERK2 →	+0.310	+2.824	.006	.034	3	2
UCEC	EGFR_pY1068 →	-0.258	-1.807	.012	.027	3	1
UCEC	JNK2 →	+0.199	+3.179	.015	.010	3	1
UCEC	Ku80 →	+0.329	+2.335	<.001	.003	3	1
UCEC	MEK1 →	+0.396	+2.807	.008	.003	3	1
UCEC	mTOR_pS2448 →	-0.156	-3.308	.011	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

ERK2 by CD300C expression — SKCM

Explore this box plot interactively →