CD2BP2

Across TCGA patient cohorts, CD2BP2 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD2BP2-associated genes across cancer lineages are FoxM1, INPP4B, and Ku80. Each is linked with CD2BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD2BP2-to-partner and partner-to-CD2BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by CD2BP2-low versus CD2BP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD2BP2→partner) and Y-score (partner→CD2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.323	+3.321	.017	.010	3	1
UCEC	INPP4B →	-0.401	-3.169	.018	.019	3	1
UCEC	Ku80 →	+0.272	+2.183	.028	.035	3	1
UCEC	mTOR_pS2448 →	-0.203	-2.980	.009	.036	2	2
UCEC	PREX1 →	-0.289	-3.321	.044	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.726	+2.827	.019	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

FoxM1 by CD2BP2 expression — UCEC

Explore this box plot interactively →