Across TCGA patient cohorts, CD2AP protein abundance is significantly associated with the RNA expression of many other genes, with 15,459 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD2AP-associated genes across cancer lineages are KIF7, ENPP4, and UBR2. Each is linked with CD2AP in more than 6 cancer types. Because this analysis shows association rather than direction, both CD2AP-to-partner and partner-to-CD2AP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD2AP→partner) and Y-score (partner→CD2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF7 →	-0.697	-0.297	<.001	.001	3	7
BRCA	ENPP4 →	+0.982	+0.311	<.001	<.001	3	7
LSCC	UBR2 →	+0.404	+0.238	<.001	<.001	3	6
LSCC	EFS →	-0.987	-0.274	<.001	.005	3	5
BRCA	PDLIM7 →	-0.853	-0.403	.001	<.001	3	5
OV	CLIC1 →	+0.750	+0.395	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,459 associations by consensus.

Exploration

CD2AP survival (RNA) · tumor vs normal (RNA) · all CD2AP data types