CD2AP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD2AP mutation is significantly associated with the RNA expression of many other genes, with 4,680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD2AP-associated genes across cancer lineages are UBTFL10, SLC36A4, and MEX3D. Each is linked with CD2AP in more than 1 cancer types. Because this analysis shows association rather than direction, both CD2AP-to-partner and partner-to-CD2AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD2AP→partner) and Y-score (partner→CD2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMUBTFL10 →+0.053+3.545<.001<.00132
UCECSLC36A4 →+0.771+1.893<.001<.00132
UCECMEX3D →+0.581+2.684<.001<.00132
UCECCDCA2 →+1.011+2.857<.001<.00132
UCECBRI3BP →+0.835+3.964<.001<.00132
SKCMUQCRC1 →+0.440+2.591.005.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,680 associations by consensus.

Exploration