CD28

Across TCGA patient cohorts, CD28 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,258 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD28-associated proteins across cancer lineages are RCSD1, SEPTIN1, and WAS. Each is linked with CD28 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD28-to-partner and partner-to-CD28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD28 versus RCSD1 in UCEC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD28→partner) and Y-score (partner→CD28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCSD1 →	+0.702	+1.045	<.001	<.001	3	10
GBM	SEPTIN1 →	+1.041	+0.823	.001	.002	3	10
GBM	WAS →	+0.564	+0.715	<.001	<.001	3	10
OV	WIPF1 →	+0.558	+0.705	<.001	<.001	3	10
UCEC	ZAP70 →	+0.821	+1.129	<.001	<.001	3	10
HNSC	CD4 →	+0.749	+0.931	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,258 associations by consensus.

CD28 vs RCSD1 — UCEC

Explore this scatter interactively →