CD276

Across TCGA patient cohorts, CD276 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,526 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD276-associated proteins across cancer lineages are MMP14, P4HA2, and SERPINH1. Each is linked with CD276 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD276-to-partner and partner-to-CD276 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD276 versus MMP14 in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD276→partner) and Y-score (partner→CD276) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP14 →	+0.677	+0.674	<.001	<.001	3	9
GBM	P4HA2 →	+0.802	+0.529	<.001	<.001	3	9
GBM	SERPINH1 →	+0.533	+0.582	<.001	<.001	3	8
CCRCC	COL5A1 →	+0.778	+0.497	<.001	<.001	3	8
BRCA	CRTAP →	+0.526	+0.541	<.001	<.001	3	8
CCRCC	CTHRC1 →	+0.836	+0.459	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,526 associations by consensus.

CD276 vs MMP14 — GBM

Explore this scatter interactively →