CD276

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD276 protein abundance is significantly associated with the RNA expression of many other genes, with 14,681 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD276-associated genes across cancer lineages are MXRA5, COL5A1, and CHSY1. Each is linked with CD276 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD276-to-partner and partner-to-CD276 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD276 versus MXRA5 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD276→partner) and Y-score (partner→CD276) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMXRA5 →+1.507+0.444<.001<.00139
BRCACOL5A1 →+1.803+0.581<.001<.00139
PDACCHSY1 →+0.619+0.514<.001<.00139
LUADLOXL2 →+1.129+0.537<.001<.00139
GBMCOL6A2 →+1.771+0.457<.001<.00139
OVADAM12 →+1.585+0.420<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,681 associations by consensus.

CD276 vs MXRA5 — OV

Per-sample scatter of CD276 vs MXRA5 in OV (Pearson r = 0.46).

Explore this scatter interactively →

Exploration