CD276

Across TCGA cell cohorts, CD276 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,062 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CD276-associated GO terms across cancer lineages are Viral process, Proteoglycan catabolic process, and Schwann cell differentiation. Each is linked with CD276 in more than 14 cancer types. Because this analysis shows association rather than direction, both CD276-to-partner and partner-to-CD276 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by CD276-low versus CD276-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD276→partner) and Y-score (partner→CD276) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral process →	+0.083	+1.061	<.001	<.001	3	15
BONE	Proteoglycan catabolic process →	+0.269	+1.476	<.001	<.001	3	13
LARGE_INTESTINE	Schwann cell differentiation →	+0.129	+1.410	<.001	<.001	3	12
STOMACH	Negative regulation of myoblast fusion →	+0.124	+2.149	.001	<.001	3	12
BLOOD_Leukemia	Regulation of intralumenal vesicle formation →	+0.148	+1.797	<.001	<.001	3	12
BONE	Heparan sulfate proteoglycan metabolic process →	+0.112	+1.066	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,062 associations by consensus.

Viral process by CD276 expression — BONE

Explore this box plot interactively →