CD248

Across TCGA patient cohorts, CD248 protein abundance is significantly associated with the RNA expression of many other genes, with 14,364 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CD248-associated genes across cancer lineages are PCOLCE, COL1A1, and PDGFRB. Each is linked with CD248 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD248-to-partner and partner-to-CD248 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD248 versus PCOLCE in OV, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD248→partner) and Y-score (partner→CD248) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+1.431	+0.816	<.001	<.001	3	10
OV	COL1A1 →	+2.886	+0.905	<.001	<.001	3	10
OV	PDGFRB →	+1.782	+0.941	<.001	<.001	3	10
OV	COL5A1 →	+2.336	+0.948	<.001	<.001	3	10
OV	LRRC32 →	+1.108	+0.725	<.001	<.001	3	10
OV	FBN1 →	+1.838	+1.027	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,364 associations by consensus.

CD248 vs PCOLCE — OV

Explore this scatter interactively →