CD248

Across TCGA cell cohorts, CD248 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,600 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD248-associated GO terms across cancer lineages are Regulation of establishment of blood-brain barrier, mRNA transport, and Negative regulation of post-translational protein modification. Each is linked with CD248 in more than 6 cancer types. Because this analysis shows association rather than direction, both CD248-to-partner and partner-to-CD248 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of establishment of blood-brain barrier grouped by CD248-low versus CD248-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD248→partner) and Y-score (partner→CD248) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of establishment of blood-brain barrier →	+0.777	+1.014	<.001	.003	3	7
BLOOD_Leukemia	mRNA transport →	+0.092	+1.610	<.001	<.001	3	7
PANCREAS	Negative regulation of post-translational protein modification →	+0.063	+0.085	<.001	.001	3	6
SOFT_TISSUE	Regulation of DNA-templated transcription initiation →	+0.054	+1.882	.001	.008	3	6
BLOOD_Leukemia	Aorta development →	+0.163	+1.457	<.001	.003	3	6
BLOOD_Leukemia	Regulation of transforming growth factor beta receptor signaling pathway →	+0.020	+0.985	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,600 associations by consensus.

Regulation of establishment of blood-brain barrier by CD248 expression — CNS

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