CD248

Across TCGA cell cohorts, CD248 mutation is significantly associated with the RNA expression of many other genes, with 380 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD248-associated genes across cancer lineages are FAM181A, LRIT2, and CABS1. Each is linked with CD248 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD248-to-partner and partner-to-CD248 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM181A grouped by CD248-low versus CD248-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD248→partner) and Y-score (partner→CD248) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	FAM181A →	+0.123	+5.000	<.001	.005	3	1
URINARY_TRACT	LRIT2 →	+0.036	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	CABS1 →	+0.012	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1A2 →	+0.023	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.011	+4.887	.009	.009	3	1
LUNG_NSCLC_LUAD	DEFA3 →	+0.176	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 380 associations by consensus.

FAM181A by CD248 expression — KIDNEY

Explore this box plot interactively →