Across TCGA cell cohorts, CD247 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD247-associated genes across cancer lineages are GFRA4, ACSM6, and CFHR2. Each is linked with CD247 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD247-to-partner and partner-to-CD247 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD247→partner) and Y-score (partner→CD247) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GFRA4 →	+0.021	+3.930	<.001	.003	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.169	<.001	.007	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

CD247 survival (RNA) · tumor vs normal (RNA) · all CD247 data types