CD244

Across TCGA cell cohorts, CD244 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,840 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD244-associated GO terms across cancer lineages are Regulation of respiratory gaseous exchange by nervous system process, Galactolipid biosynthetic process, and Galactosylceramide biosynthetic process. Each is linked with CD244 in more than 4 cancer types. Because this analysis shows association rather than direction, both CD244-to-partner and partner-to-CD244 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of respiratory gaseous exchange by nervous system process grouped by CD244-low versus CD244-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD244→partner) and Y-score (partner→CD244) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of respiratory gaseous exchange by nervous system process →	-0.766	-0.116	<.001	<.001	3	5
BLOOD_Lymphoma	Galactolipid biosynthetic process →	-0.683	-1.053	.001	.008	3	4
BLOOD_Lymphoma	Galactosylceramide biosynthetic process →	-0.683	-1.053	.001	.008	3	4
BLOOD_Lymphoma	Negative regulation of T cell apoptotic process →	+0.126	+1.818	<.001	<.001	3	4
BLOOD_Leukemia	Positive regulation of T cell proliferation →	+0.087	+1.728	<.001	.002	3	4
BLOOD_Leukemia	Negative regulation of tyrosine phosphorylation of STAT protein →	-0.066	-1.155	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

Regulation of respiratory gaseous exchange by nervous system process by CD244 expression — SKIN

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