CD244

Across TCGA cell cohorts, CD244 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD244-associated genes across cancer lineages are CST9L, C20orf85, and CFHR5. Each is linked with CD244 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD244-to-partner and partner-to-CD244 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9L grouped by CD244-low versus CD244-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD244→partner) and Y-score (partner→CD244) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CST9L →	+0.383	+4.269	<.001	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.018	+4.384	.001	.006	3	1
BLOOD_Leukemia	CFHR5 →	+0.003	+4.384	<.001	.006	3	1
BLOOD_Leukemia	OR13C9 →	+0.038	+3.551	<.001	.009	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.076	+3.705	<.001	.007	3	1
BLOOD_Leukemia	OR4K2 →	+0.025	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

CST9L by CD244 expression — BLOOD_Leukemia

Explore this box plot interactively →