CD22

Across TCGA patient cohorts, CD22 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,636 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD22-associated proteins across cancer lineages are DOCK10, NFATC2, and WAS. Each is linked with CD22 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD22-to-partner and partner-to-CD22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD22 versus DOCK10 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD22→partner) and Y-score (partner→CD22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK10 →	+0.473	+1.046	<.001	<.001	3	9
HNSC	NFATC2 →	+0.401	+0.717	<.001	<.001	3	8
LSCC	WAS →	+0.478	+1.166	<.001	<.001	3	8
BRCA	EVL →	+0.709	+0.840	<.001	<.001	3	8
BRCA	EVL_S246 →	+0.801	+0.770	<.001	<.001	3	8
LSCC	IL16 →	+0.664	+1.171	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,636 associations by consensus.

CD22 vs DOCK10 — LSCC

Explore this scatter interactively →