CD209

Across TCGA patient cohorts, CD209 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD209-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-B1, and Syk. Each is linked with CD209 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD209-to-partner and partner-to-CD209 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CD209-low versus CD209-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD209→partner) and Y-score (partner→CD209) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.131	+2.178	.002	.035	3	4
UCEC	Cyclin-B1 →	+0.620	+1.584	<.001	.009	3	4
LUSC	Syk →	+0.474	+2.816	.018	.036	3	3
UCEC	C-Raf →	+0.133	+1.321	.005	.029	3	3
COAD	eEF2 →	+0.279	+2.178	.045	.035	3	2
COAD	EGFR_pY1068 →	-0.403	-3.157	.008	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Caspase-7-cleavedD198 by CD209 expression — COAD

Explore this box plot interactively →