CD209

Across TCGA cell cohorts, CD209 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CD209-associated genes across cancer lineages are ADGRE3, SPRR2F, and TAAR8. Each is linked with CD209 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD209-to-partner and partner-to-CD209 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADGRE3 grouped by CD209-low versus CD209-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD209→partner) and Y-score (partner→CD209) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ADGRE3 →	+0.108	+4.212	<.001	.007	3	1
LARGE_INTESTINE	SPRR2F →	+0.564	+3.707	.001	.009	3	1
STOMACH	TAAR8 →	+0.030	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	P2RY13 →	+0.020	+4.312	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ADGRE3 by CD209 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →