CD207

Across TCGA patient cohorts, CD207 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD207-associated genes across cancer lineages are STAT3_pY705, FoxM1, and INPP4B. Each is linked with CD207 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD207-to-partner and partner-to-CD207 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by CD207-low versus CD207-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD207→partner) and Y-score (partner→CD207) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.404	-2.990	<.001	<.001	3	3
UCEC	FoxM1 →	+0.234	+2.087	.018	.005	3	2
UCEC	INPP4B →	-0.368	-3.700	.002	.001	3	2
UCEC	Notch1 →	+0.186	+2.584	<.001	.001	3	2
UCEC	p38-MAPK →	-0.155	-2.095	.014	.017	3	2
UCEC	Caspase-7-cleavedD198 →	+0.671	+2.087	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

STAT3_pY705 by CD207 expression — UCEC

Explore this box plot interactively →