CD200R1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD200R1 mutation is significantly associated with the RNA expression of many other genes, with 674 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD200R1-associated genes across cancer lineages are MIR6882, PKN3, and C1orf50. Each is linked with CD200R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD200R1-to-partner and partner-to-CD200R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6882 grouped by CD200R1-low versus CD200R1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD200R1→partner) and Y-score (partner→CD200R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR6882 →+0.224+2.943<.001.00932
UCECPKN3 →+0.657+2.233.002.00632
UCECC1orf50 →+0.376+2.732<.001.00332
UCECDOLPP1 →+0.601+3.724<.001<.00132
UCECCDT1 →+0.660+2.939.008<.00132
UCECSHMT1 →+0.624+2.906.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 674 associations by consensus.

MIR6882 by CD200R1 expression — SKCM

Box plot of MIR6882 in CD200R1-low vs CD200R1-high samples in SKCM.

Explore this box plot interactively →

Exploration