CD200R1

Across TCGA patient cohorts, CD200R1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD200R1-associated genes across cancer lineages are Cyclin-E2, Chk2_pT68, and eEF2K. Each is linked with CD200R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD200R1-to-partner and partner-to-CD200R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by CD200R1-low versus CD200R1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD200R1→partner) and Y-score (partner→CD200R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Cyclin-E2 →	+0.140	+2.816	.046	.036	3	2
UCEC	Chk2_pT68 →	-0.188	-2.973	.037	.035	3	2
COAD	eEF2K →	+0.462	+2.846	.009	.033	3	2
SKCM	STAT5a →	+0.705	+3.169	.019	.019	3	1
UCEC	p62 Lck ligand →	+0.472	+2.459	.002	.020	3	1
UCEC	Annexin-1 →	+0.548	+2.827	.031	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Cyclin-E2 by CD200R1 expression — LUSC

Explore this box plot interactively →