CD2

Across TCGA cell cohorts, CD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,769 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CD2-associated GO terms across cancer lineages are Germinal center B cell differentiation, Positive regulation of behavior, and Epithelial tube morphogenesis. Each is linked with CD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD2-to-partner and partner-to-CD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Germinal center B cell differentiation grouped by CD2-low versus CD2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD2→partner) and Y-score (partner→CD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Germinal center B cell differentiation →	-0.242	-2.235	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of behavior →	-0.123	-2.063	<.001	<.001	3	4
OESOPHAGUS	Epithelial tube morphogenesis →	-0.048	-0.034	.001	.009	3	4
BLOOD_Lymphoma	Glutaminyl-tRNAGln biosynthesis via transamidation →	-0.085	-3.404	<.001	<.001	3	4
BLOOD_Lymphoma	Beige fat cell differentiation →	-0.146	-2.481	<.001	<.001	3	4
CNS	Regulation of protein homooligomerization →	-0.124	-0.017	.004	.004	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,769 associations by consensus.

Germinal center B cell differentiation by CD2 expression — BLOOD_Leukemia

Explore this box plot interactively →