CD1E

Across TCGA patient cohorts, CD1E mutation is significantly associated with the RNA expression of many other genes, with 3,078 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD1E-associated genes across cancer lineages are MIR6894, RPL32P8, and TOMM5. Each is linked with CD1E in more than 3 cancer types. Because this analysis shows association rather than direction, both CD1E-to-partner and partner-to-CD1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by CD1E-low versus CD1E-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1E→partner) and Y-score (partner→CD1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6894 →	+0.538	+5.091	<.001	<.001	3	4
BRCA	RPL32P8 →	+0.181	+4.995	.005	<.001	3	4
LUAD	TOMM5 →	+0.573	+3.632	<.001	.001	3	4
LUAD	OR4D7P →	+0.008	+3.754	<.001	.009	3	4
UCEC	GOT1 →	+0.488	+3.931	<.001	<.001	3	4
PRAD	TUBB4BP1 →	+0.262	+6.593	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

MIR6894 by CD1E expression — BRCA

Explore this box plot interactively →