CD1E

Across TCGA cell cohorts, CD1E RNA expression is significantly associated with the go_rna of many other GO terms, with 1,669 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD1E-associated GO terms across cancer lineages are Lysosome organization, Lytic vacuole organization, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with CD1E in more than 6 cancer types. Because this analysis shows association rather than direction, both CD1E-to-partner and partner-to-CD1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosome organization grouped by CD1E-low versus CD1E-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1E→partner) and Y-score (partner→CD1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Lysosome organization →	+0.041	+0.054	.004	.007	3	7
LUNG_NSCLC_LUSC	Lytic vacuole organization →	+0.041	+0.054	.004	.007	3	7
SKIN	Negative regulation of mRNA splicing, via spliceosome →	+0.071	+0.038	<.001	<.001	3	6
BLOOD_Leukemia	Protein polyubiquitination →	+0.018	+1.512	.001	.005	3	6
SKIN	Negative regulation of protein binding →	+0.089	+0.038	<.001	.002	3	5
SKIN	Actomyosin contractile ring organization →	+0.105	+0.041	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,669 associations by consensus.

Lysosome organization by CD1E expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →