CD1E

Across TCGA cell cohorts, CD1E mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD1E-associated genes across cancer lineages are MMP26, OR10G2, and SPATA31A5. Each is linked with CD1E in more than 1 cancer types. Because this analysis shows association rather than direction, both CD1E-to-partner and partner-to-CD1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by CD1E-low versus CD1E-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1E→partner) and Y-score (partner→CD1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	2
BLOOD_Leukemia	OR10G2 →	+1.565	+4.551	<.001	.004	3	2
LUNG_SCLC	SPATA31A5 →	+0.013	+5.029	<.001	.006	3	1
LUNG_NSCLC_LUAD	MPC1L →	+0.095	+4.371	<.001	.005	3	1
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
STOMACH	OR1A2 →	+0.023	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MMP26 by CD1E expression — BLOOD_Myeloma

Explore this box plot interactively →