CD1D

Across TCGA cell cohorts, CD1D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,990 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CD1D-associated GO terms across cancer lineages are Antigen processing and presentation of lipid antigen via MHC class Ib, Antigen processing and presentation, endogenous lipid antigen via MHC class Ib, and Antigen processing and presentation, exogenous lipid antigen via MHC class Ib. Each is linked with CD1D in more than 19 cancer types. Because this analysis shows association rather than direction, both CD1D-to-partner and partner-to-CD1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of lipid antigen via MHC class Ib grouped by CD1D-low versus CD1D-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1D→partner) and Y-score (partner→CD1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Antigen processing and presentation of lipid antigen via MHC class Ib →	+1.076	+1.725	<.001	<.001	3	20
BLOOD_Leukemia	Antigen processing and presentation, endogenous lipid antigen via MHC class Ib →	+1.076	+1.725	<.001	<.001	3	20
BLOOD_Leukemia	Antigen processing and presentation, exogenous lipid antigen via MHC class Ib →	+1.076	+1.725	<.001	<.001	3	20
SKIN	Protein folding →	+0.054	+0.824	<.001	<.001	3	10
OVARY	Negative regulation of myoblast fusion →	+0.104	+0.354	<.001	<.001	3	8
SKIN	Axoneme assembly →	-0.032	-0.580	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,990 associations by consensus.

Antigen processing and presentation of lipid antigen via MHC class Ib by CD1D expression — BLOOD_Leukemia

Explore this box plot interactively →