CD1D

Across TCGA cell cohorts, CD1D mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD1D-associated genes across cancer lineages are DAZ4, VSIG4, and LRRC10. Each is linked with CD1D in more than 1 cancer types. Because this analysis shows association rather than direction, both CD1D-to-partner and partner-to-CD1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ4 grouped by CD1D-low versus CD1D-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1D→partner) and Y-score (partner→CD1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAZ4 →	+0.123	+3.240	.004	.004	3	2
LARGE_INTESTINE	VSIG4 →	+0.026	+2.791	<.001	.005	3	1
LARGE_INTESTINE	LRRC10 →	+0.012	+3.425	<.001	<.001	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.041	+3.257	.002	.001	3	1
LARGE_INTESTINE	C16orf96 →	+0.462	+3.652	.005	.001	3	1
SKIN	MS4A6E →	+0.054	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

DAZ4 by CD1D expression — LARGE_INTESTINE

Explore this box plot interactively →