CD1C

Across TCGA cell cohorts, CD1C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD1C-associated GO terms across cancer lineages are Regulation of complement activation, Homologous recombination, and Antigen processing and presentation of lipid antigen via MHC class Ib. Each is linked with CD1C in more than 3 cancer types. Because this analysis shows association rather than direction, both CD1C-to-partner and partner-to-CD1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of complement activation grouped by CD1C-low versus CD1C-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1C→partner) and Y-score (partner→CD1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of complement activation →	-0.282	-1.863	<.001	<.001	3	4
BLOOD_Lymphoma	Homologous recombination →	+0.048	+1.273	<.001	<.001	3	4
BLOOD_Lymphoma	Antigen processing and presentation of lipid antigen via MHC class Ib →	+0.903	+1.741	<.001	<.001	3	4
BLOOD_Lymphoma	Antigen processing and presentation, endogenous lipid antigen via MHC class Ib →	+0.903	+1.741	<.001	<.001	3	4
BLOOD_Lymphoma	Antigen processing and presentation, exogenous lipid antigen via MHC class Ib →	+0.903	+1.741	<.001	<.001	3	4
BLOOD_Lymphoma	Detoxification →	-0.069	-1.255	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,615 associations by consensus.

Regulation of complement activation by CD1C expression — BLOOD_Lymphoma

Explore this box plot interactively →