CD19

Across TCGA patient cohorts, CD19 protein abundance is significantly associated with the RNA expression of many other genes, with 10,535 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD19-associated genes across cancer lineages are PIK3CG, FBXW7, and CYTIP. Each is linked with CD19 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD19-to-partner and partner-to-CD19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD19 versus PIK3CG in HNSC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD19→partner) and Y-score (partner→CD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PIK3CG →	+2.665	+1.092	.001	.003	3	3
HNSC	FBXW7 →	+0.968	+0.759	.005	.005	3	3
HNSC	CYTIP →	+3.410	+1.091	.001	.003	3	3
HNSC	COQ6 →	-0.858	-0.760	.002	.005	3	3
HNSC	FLT3 →	+1.550	+0.919	<.001	.005	3	3
HNSC	LAX1 →	+3.435	+1.083	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,535 associations by consensus.

CD19 vs PIK3CG — HNSC

Explore this scatter interactively →