CD19

Across TCGA patient cohorts, CD19 mutation is significantly associated with the RNA expression of many other genes, with 2,280 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD19-associated genes across cancer lineages are RNY4P23, MIR8053, and COPS4. Each is linked with CD19 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD19-to-partner and partner-to-CD19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P23 grouped by CD19-low versus CD19-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD19→partner) and Y-score (partner→CD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNY4P23 →	+0.434	+3.193	<.001	.006	3	4
STAD	MIR8053 →	+0.492	+3.745	<.001	.005	3	3
UCEC	COPS4 →	+0.441	+1.890	.008	.005	3	3
UCEC	ATP6V1B2 →	+0.484	+2.156	.001	.009	3	3
UCEC	CCL5 →	+1.208	+2.823	<.001	.001	3	2
UCEC	SRCIN1 →	-0.849	-3.796	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,280 associations by consensus.

RNY4P23 by CD19 expression — BLCA

Explore this box plot interactively →