CD19

Across TCGA cell cohorts, CD19 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD19-associated genes across cancer lineages are SCGB1A1, NPY2R, and ARGFX. Each is linked with CD19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD19-to-partner and partner-to-CD19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1A1 grouped by CD19-low versus CD19-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD19→partner) and Y-score (partner→CD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SCGB1A1 →	+0.192	+3.714	<.001	.004	3	1
LARGE_INTESTINE	NPY2R →	+0.004	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ARGFX →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.195	+3.688	<.001	.002	3	1
LARGE_INTESTINE	FCGR3A →	+0.186	+3.347	<.001	.005	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SCGB1A1 by CD19 expression — LARGE_INTESTINE

Explore this box plot interactively →